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RNA NanoMed
Due to the rapid growth of the field of RNA and its potential applications including RNA therapeutics, it is encouraging to have an RNA journal that advances the field by bridging the fundamental research and application of RNA. The prediction that RNA will become the third milestone in drug development has become a reality. The establishment of an RNA journal related to this field by the International Society for RNA Nanotechnology and Nanomedicine (ISRNN) will be in line with the vision and mission of the society.
About Us
Editorial for the Inaugural Issue
The recent discovery of the critical role of RNA in biological systems has revolutionized our understanding of molecular biology. It was found that only 1.5% of the human genome encodes for proteins, while the remaining 98.5% mainly codes for small or long non-coding RNA. These unexpected findings have significantly transformed life sciences. Recent FDA approval of RNAi drugs and COVID-19 mRNA vaccines has highlighted the potential of RNA therapeutics in clinics. These breakthroughs underscore RNA's emergence as a cornerstone of modern medicine.
Current Issue
Volume 2 Issue 2
Original Research Articles
APOBEC3G in complex with RNA: bridging high-speed AFM and simulation studies
Mohtadin Hashemi, Yangang Pan, Luda S. Shlyakhtenko, Yuri L. Lyubchenko
ISRNN (RNA NanoMed.)
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Lipid nanoparticles for combined osteogenic differentiation and stem cell tracking
Ping Song, Jørgen Kjems
ISRNN (RNA NanoMed.)
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Review Articles
RNA Aptamer Discovery: SELEX Methods and Emerging Strategies
Andrew Michael Reynolds, Xiaohong Tan
ISRNN (RNA NanoMed.)
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Engineering synthetic RNA-based condensates with tunable chemical properties
Denis Victorov, Jaimie Marie Stewart
ISRNN (RNA NanoMed.)
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Three-way Junction RNA Nanoparticles for Targeted Drug Delivery to Cancer
Yanghao Li, Xu Yang, Bin Guo
ISRNN (RNA NanoMed.)
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Previous Issues
Volume 2 - Issue 1
Original Research Articles
Targeting EGFR self-assembling RNA nanoparticles co-delivering paclitaxel and miRNA21 inhibitors for the treatment of head and neck tumors
Yuejuan Che, Zhuohao Wen, Jiali Shou, Yujuan Li*, Miao Zhou*, Chang Du*
RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis
Daniel W. Binzel, Congcong Xu, Katherine Binzel, Arijit Ghosh, Adam Pippin, Xin Li, Mario Sechi, Michael V. Knopp, Krishan Kumar, Peixuan Guo*
CD133-Guided RNA Nanoparticle Delivery of FTO siRNA Impairs Leukemia Resistance to Tyrosine Kinase Inhibitor Therapy
Huiqin Bian, Changli Zhou, Hiroaki Koyama, Wen Gao, Sicheng Bian, Tao Cheng, Xiaonan Han, William Tse, Alexander Miron, Shujun Liu*
Review Articles
Nucleic-Acid Based Approaches for Detection of microRNA
Akhilesh Kumar Gupta, Alexey V. Krasnoslobodtsev*
Leveraging Immunological Properties of Nucleic Acid Nanoparticles to Improve Cancer Therapy
Tanvi S. Bolarum and Marina A. Dobrovolskaia*
Volume 1 - Issue 1
Original Research Articles
Co-incubation of Short Amphiphilic Peptides with Dicer Substrate RNAs Results in β-Sheet Fibrils for Enhanced Gene Silencing in Cancer Cells
Kshitij Gupta, Lorena Parlea, Mathias Viard, Katelyn Smith, Anu Puri, Joseph T. Bergman, Taejin Kim, Bruce A. Shapiro*
The Reduction of Traumatic Spinal Cord Secondary Injury by Anti-RhoA siRNA Functionalized Nucleic Acid Nanoparticles (NANPs)
Damian Beasock, Morgan Chandler, Yasmine Radwan, Zhen Liao, Fuying Ma, Ken Webb, Martin Panigaj, Jeoung Soo Lee, Kirill A. Afonin*
pH-responsive bond as a linker for the release of chemical drugs from RNA–drug complexes in endosome or lysosome
Piotr Rychahou, Sijin Guo, Yinan Zhang, Nicole Rychagov, Yekaterina Y. Zaytseva, Heidi L. Weiss, B. Mark Evers, Peixuan Guo*
Conversion of Chemical Drugs into Targeting Ligands on RNA Nanoparticles and Assessing Payload Stoichiometry for Optimal Biodistribution in Cancer Treatment
Congcong Xu, Hongran Yin, Tesla Yudhistira, Zhefeng Li, Daniel W. Binzel, Peixuan Guo*
Review Articles
Harnessing Computational Approaches for RNA-Targeted Drug Discovery
Yuanzhe Zhou, Shi-Jie Chen*
Targeted Delivery of Potent Chemical Drugs and RNAi to Drug-Resistant Breast Cancer Using RNA-Nanotechnology and RNA-Ligand Displaying Extracellular vesicles
Yuan-Soon Ho, Tzu-Chun Cheng, Peixuan Guo*
Applications of Surface Plasmon Resonance for Advanced Studies Involving Nucleic Acids
Katelynn Pranger, Kenya Rosas, Dmitriy Khon, Emil F. Khisamutdinov*
